SLC10A1 Human shRNA Plasmid Kit (Locus ID 6554)
SKU
TL309420
SLC10A1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 6554 |
|---|---|
| Synonyms | FHCA2; NTCP |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | SLC10A1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 6554). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_003049, NM_003049.1, NM_003049.2, NM_003049.3, BC069799, BC069822, BC074724, BC126298, BC136355, NM_003049.4 |
| UniProt ID | Q14973 |
| Summary | The protein encoded by this gene belongs to the sodium/bile acid cotransporter family, which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen, bile duct and kidney, and the liver-specific sodium/bile acid cotransporter, represented by this protein, that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism, hence this protein is important for cholesterol homeostasis. provided by RefSeq, Oct 2011 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
N-linked glycosylation is not essential for sodium taurocholate cotransporting polypeptide to mediate hepatitis B virus infection in vitro
Lee, Zong, Krotow et al
J. Virol. (2018)
Lee, Zong, Krotow et al
J. Virol. (2018)
AI Summary: OriGene’s lentiviruses encoding 29mer shRNAs against human NTCP (product TL309420V) and scrambled control shRNA were used to knock down NTCP expression in differentiated HepaRG cells, enabling the study of NTCP’s role in hepatitis B virus infection.
Snippet: Lentiviruses encoding 432 four 29mer shRNAs against human NTCP (TL309420V) or scrambled control shRNA were 433 purchased from Origene. Differentiated HepaRG cells seeded in 96-well plates were infected 434 overnight with lentivirus at M.O.I. of 100, in the presence of 8ug/ml of polybrene. Medium was 435 changed next day and cells were harvested 4 days post-infection
Showing 1-1 of 1 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
