Stanniocalcin 2 (STC2) Human shRNA Plasmid Kit (Locus ID 8614)
SKU
TL309053
STC2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
2 Weeks*
Specifications
| Product Data | |
| Locus ID | 8614 |
|---|---|
| Synonyms | STC-2; STCRP |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | STC2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 8614). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_003714, NM_003714.1, NM_003714.2, BC000658, BC006352, BC013958 |
| UniProt ID | O76061 |
| Summary | This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
A Hypoxia Associated STC2 High Endothelial Subpopulation is Linked to Lipid Metabolic Reprogramming, Pathological Angiogenesis, and Immune Remodeling in Head and Neck Squamous Cell Carcinoma
Chen, Qin, Liu et al
Int J Gen Med (2026) 19, 619908 DOI: 10.2147/IJGM.S619908
Chen, Qin, Liu et al
Int J Gen Med (2026) 19, 619908 DOI: 10.2147/IJGM.S619908
AI Summary: OriGene's STC2 Human shRNA Plasmid Kit (Cat# TL309053) and scrambled shRNA negative control (TR30021) were used to knock down STC2 expression in HUVECs, enabling the study to assess the functional role of STC2 in endothelial cell viability, migration, and angiogenesis in head and neck squamous cell carcinoma.
Snippet: d 0.03–0.05 mg/mL endothelial cell growth supplement (ECGS) at 37 °C with 5% CO2.For STC2 knockdown, HUVECs were transfected with the STC2 Human shRNA Plasmid Kit (Cat# TL309053, Origene, USA), which contained four distinct 29-mer shRNA lentiviral GFP constructs targeting human STC2 (Gene ID: 8614) and a scrambled non-targeting shRNA negative control (TR30021) provided by the
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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