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TRIM32 Human shRNA Plasmid Kit (Locus ID 22954)

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SKU
TL308646
TRIM32 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*

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Other products for "TRIM32 or NM_001099679"

Specifications
Specifications
Product Data
Locus ID 22954
Synonyms BBS11; HT2A; LGMD2H; LGMDR8; TATIP
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components TRIM32 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 22954). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001099679, NM_012210, NM_012210.1, NM_012210.2, NM_012210.3, NM_001099679.1, BC003154, NM_001099679.2, NM_012210.4
UniProt ID Q13049
Summary The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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Documents
Resources

file-alt Citations

Trim32 suppresses cerebellar development and tumorigenesis by degrading Gli1/sonic hedgehog signaling
Wang, Luo, Zhang et al
Cell Death Differ. (2019)
AI Summary: In this study, OriGene’s mouse Trim32 cDNA clone (Cat# MR206482) and mouse Gli1 cDNA clone (Cat# MR207701) were used to investigate how Trim32 regulates SHH signaling and suppresses cerebellar tumorigenesis by promoting the degradation of Gli1.
Snippet: Trim32 suppresses cerebellar development and tumorigenesis by degrading Gli1/sonic hedgehog signaling
Showing 1-1 of 1 papers.
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