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TRPC6 Human shRNA Plasmid Kit (Locus ID 7225)

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SKU
TL308626
TRPC6 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*

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Other products for "TRPC6 or NM_004621"

Specifications
Specifications
Product Data
Locus ID 7225
Synonyms FSGS2; TRP6
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components TRPC6 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 7225). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_004621, NM_004621.1, NM_004621.2, NM_004621.3, NM_004621.4, NM_004621.5, BC093658, BC093658.1, BC093660
UniProt ID Q9Y210
Summary The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). provided by RefSeq, Mar 2009
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Rhotekin-1 is a novel interacting protein and regulator of TRPC6 activity
Lavanderos, Orellana-Serradell, Maureira et al
FEBS J (2025)
Cited by 2
AI Summary: OriGene products, specifically the Myc-DDK-RTKN-1 plasmid (#MR208745) and shRNAs against human TRPC6 (#TL308626), were used in this study to manipulate RTKN-1 and TRPC6 expression, enabling the investigation of their roles and interactions in regulating TRPC6 activity and cell function.
Snippet: mbly protocol [[61]] with the hTRPC6-YFP plasmid and jGCaMP8f (obtained via Addgene plasmid #162373 [[33]]) as templates. … Plasmids encoding the shRNAs against human TRPC6 and myc-DDK-RTKN-1 plasmids were purchased from Origene Inc. (catalogs #TL308626 and #MR208745, respectively). …
Showing 1-1 of 1 papers.
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