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TTC3 Human shRNA Plasmid Kit (Locus ID 7267)

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SKU
TL308587
TTC3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 7267
Synonyms DCRR1; RNF105; TPRDIII
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components TTC3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 7267). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC026260, NM_001001894, NM_003316, NM_001320703, NM_001320704, NM_001330681, NM_001330682, NM_001330683, NM_001353936, NM_001353937, NM_001353938, NM_003316.1, NM_003316.2, NM_003316.3, NM_001001894.1, NM_001001894.2, BC047867, BC063033, BC092466, BC137345, NM_003316.4
UniProt ID P53804
Summary E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation; its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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