USP5 Human shRNA Plasmid Kit (Locus ID 8078)
Specifications
| Product Data | |
| Locus ID | 8078 |
|---|---|
| Synonyms | ISOT |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | USP5 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 8078). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC005139, NM_001098536, NM_003481, NM_003481.1, NM_003481.2, NM_001098536.1, BC005139.2, BC004889, NM_001098536.2, NM_003481.3 |
| UniProt ID | P45974 |
| Summary | Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 PubMed 7578059).supplied by OMIM, Mar 2010 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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