UVRAG Human shRNA Plasmid Kit (Locus ID 7405)
Specifications
| Product Data | |
| Locus ID | 7405 |
|---|---|
| Synonyms | DHTX; p63; VPS38 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | UVRAG - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 7405). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_003369, NM_003369.1, NM_003369.2, NM_003369.3, BC064837, BC013176, NM_003369.4 |
| UniProt ID | Q9P2Y5 |
| Summary | This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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