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Vimentin (VIM) Human shRNA Plasmid Kit (Locus ID 7431)

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SKU
TL308419
VIM - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 7431
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components VIM - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 7431). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_003380, NM_003380.1, NM_003380.2, NM_003380.3, BC000163, BC000163.2, BC030573, BC031031, BC066956, NM_003380.5
UniProt ID P08670
Summary This gene encodes a type III intermediate filament protein. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The encoded protein is responsible for maintaining cell shape and integrity of the cytoplasm, and stabilizing cytoskeletal interactions. This protein is involved in neuritogenesis and cholesterol transport and functions as an organizer of a number of other critical proteins involved in cell attachment, migration, and signaling. Bacterial and viral pathogens have been shown to attach to this protein on the host cell surface. Mutations in this gene are associated with congenital cataracts in human patients. provided by RefSeq, Aug 2017
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Two independent translocation modes drive neural stem cell dissemination into the human fetal cortex
Wimmer, Lestienne, Brunet et al
bioRxiv (2025)
Cited by 5
AI Summary: OriGene products, specifically shRNAs targeting Human EZR (TF308420), STK10 (TF320540), SLK (TG320620), DYNC1H1 (TL313335), RDX (TL309884), MSN (TL311375), ECT2 (TL304854), VIM (TL308419), and PAFAH1B1/LIS1 (TL310628), were used in this study to selectively knock down genes and investigate their roles in the distinct translocation modes of neural stem cells during human cortical development.
Snippet: … Benaroch), Human EZR shRNA (TF308420, Origene), Human STK10 shRNA (TF320540, Origene), Human SLK shRNA (TG320620, Origene), Human DYNC1H1 shRNA (TL313335, Origene), Human RDX shRNA (TL309884, Origene), Human MSN shRNA (TL311375, Origene), Human ECT2 shRNA (TL304854, Origene), Human VIM shRNA (TL308419, Origene), Human PAFAH1B1 (LIS1) shRNA (TL310628, Origene), Dominant Negative KASH. …
Showing 1-1 of 1 papers.
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