XRN2 Human shRNA Plasmid Kit (Locus ID 22803)

SKU
TL308334
XRN2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 22803
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components XRN2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 22803). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001317960, NM_012255, NM_012255.1, NM_012255.2, NM_012255.3, NM_012255.4, BC000315, BC006417, BC032075, BC131775, BC142960, BC160100, NM_012255.5
UniProt ID Q9H0D6
Summary This gene encodes a 5'-3' exonuclease that promotes transcription termination at cotranscriptional cleavage sites. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Dec 2015
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

XRN2 promotes EMT and metastasis through regulating maturation of miR-10a
Zhang, Lu, Chen et al
Oncogene (2017)
AI Summary: OriGene's human XRN2 shRNA was used in this study to knock down XRN2 expression, enabling the authors to investigate XRN2's role in promoting EMT and metastasis by regulating miR-10a maturation.
Snippet: The human XRN2 shRNA was from OriGene (Rockville, MD, USA). The lentivirus was produced using the ViraPower Lentiviral Expression System (Life Technologies, Carlsbad, CA, USA) according to the manufacturer's instruction. ... All 3 versions Cite SaveSaving
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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