ZNF384 Human shRNA Plasmid Kit (Locus ID 171017)

SKU
TL308178
ZNF384 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 171017
Synonyms CAGH1; CAGH1A; CIZ; ERDA2; FLJ59043; NMP4; NP; TNRC1
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components ZNF384 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 171017). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001039916, NM_001039917, NM_001039918, NM_001039919, NM_001039920, NM_001135734, NM_133476, NM_001039920.1, NM_001039920.2, NM_133476.1, NM_133476.2, NM_133476.3, NM_133476.4, NM_001039917.1, NM_001039916.1, NM_001135734.1, NM_001135734.2, NM_001039918.1, BC053361, BC053361.1, BM554320, NM_133476.5
UniProt ID Q8TF68
Summary This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. provided by RefSeq, Apr 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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