ZNF384 Human shRNA Plasmid Kit (Locus ID 171017)
Specifications
| Product Data | |
| Locus ID | 171017 |
|---|---|
| Synonyms | CAGH1; CAGH1A; CIZ; ERDA2; FLJ59043; NMP4; NP; TNRC1 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | ZNF384 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 171017). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001039916, NM_001039917, NM_001039918, NM_001039919, NM_001039920, NM_001135734, NM_133476, NM_001039920.1, NM_001039920.2, NM_133476.1, NM_133476.2, NM_133476.3, NM_133476.4, NM_001039917.1, NM_001039916.1, NM_001135734.1, NM_001135734.2, NM_001039918.1, BC053361, BC053361.1, BM554320, NM_133476.5 |
| UniProt ID | Q8TF68 |
| Summary | This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. provided by RefSeq, Apr 2011 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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