ADAM15 Human shRNA Plasmid Kit (Locus ID 8751)
Specifications
| Product Data | |
| Locus ID | 8751 |
|---|---|
| Synonyms | MDC15 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | ADAM15 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 8751). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001261464, NM_001261465, NM_001261466, NM_003815, NM_207191, NM_207194, NM_207195, NM_207196, NM_207197, NR_048577, NR_048578, NR_048579, NM_003815.1, NM_003815.2, NM_003815.3, NM_003815.4, NM_207191.1, NM_207191.2, NM_207194.1, NM_207194.2, NM_207195.1, NM_207195.2, NM_207197.1, NM_207197.2, NM_207196.1, NM_207196.2, NM_001261466.1, NM_001261465.1, NM_001261464.1, BC014566, BC014566.2, BM971880, NM_001261465.2, NM_001261466.2, NM_207196.3, NM_207197.3, NM_001261464.2, NM_207191.3, NM_207195.3, NM_207194.3, NM_003815.5 |
| UniProt ID | Q13444 |
| Summary | The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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