CBFA2T3 Human shRNA Plasmid Kit (Locus ID 863)
Specifications
| Product Data | |
| Locus ID | 863 |
|---|---|
| Synonyms | ETO2; MTG16; MTGR2; RUNX1T3; ZMYND4 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | CBFA2T3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 863). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_005187, NM_175931, NM_005187.2, NM_005187.3, NM_005187.4, NM_005187.5, NM_175931.1, NM_175931.2, BC047019, BC009554, BC062624, NM_175931.3, NM_005187.6 |
| UniProt ID | O75081 |
| Summary | This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. provided by RefSeq, Nov 2010 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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