CENPJ Human shRNA Plasmid Kit (Locus ID 55835)
Specifications
| Product Data | |
| Locus ID | 55835 |
|---|---|
| Synonyms | BM032; CENP-J; CPAP; LAP; LIP1; MCPH6; Sas-4; SASS4; SCKL4 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | CENPJ - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 55835). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_018451, NR_047594, NR_047595, NM_018451.1, NM_018451.2, NM_018451.3, NM_018451.4, BC024209, BC062675, BC092467, BC113110, BC113111, BC113662, BC113664, BC143757, BC143758, NM_018451.5 |
| UniProt ID | Q9HC77 |
| Summary | This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and cognitive disability. Alternatively spliced transcript variants have been found for this gene. provided by RefSeq, Apr 2012 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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