CTPS2 Human shRNA Plasmid Kit (Locus ID 56474)
Specifications
| Product Data | |
| Locus ID | 56474 |
|---|---|
| Synonyms | GATD5B |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | CTPS2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 56474). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001144002, NM_019857, NM_175859, NM_019857.1, NM_019857.2, NM_019857.3, NM_019857.4, NM_175859.1, NM_175859.2, NM_001144002.1, BC034986, BC034986.1, BC006256, NM_019857.5, NM_175859.3 |
| UniProt ID | Q9NRF8 |
| Summary | The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2013 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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