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DPP1 (CTSC) Human shRNA Plasmid Kit (Locus ID 1075)

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SKU
TL305175
CTSC - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*

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Other products for "DPP1 or NM_001114173"

Specifications
Specifications
Product Data
Locus ID 1075
Synonyms CPPI; DPP-I; DPP1; DPPI; HMS; JP; JPD; PALS; PDON1; PLS
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components CTSC - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 1075). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001114173, NM_001814, NM_148170, NM_001814.1, NM_001814.2, NM_001814.3, NM_001814.4, NM_001814.5, NM_148170.1, NM_148170.2, NM_148170.3, NM_148170.4, NM_001114173.1, NM_001114173.2, BC023559, BC054028, BC100891, BC100892, BC100893, BC100894, BC107770, BC109386, BC110071, BC113850, BC113897, BC146692, BM997817, NM_148170.5, NM_001114173.3
UniProt ID P53634
Summary This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. provided by RefSeq, Nov 2015
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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