DCTN3 Human shRNA Plasmid Kit (Locus ID 11258)
Specifications
| Product Data | |
| Locus ID | 11258 |
|---|---|
| Synonyms | DCTN-22; DCTN22 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | DCTN3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 11258). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001281425, NM_001281426, NM_001281427, NM_007234, NM_024348, NM_024348.1, NM_024348.2, NM_024348.3, NM_007234.1, NM_007234.2, NM_007234.3, NM_007234.4, NM_001281426.1, NM_001281425.1, NM_001281427.1, BC003004, BC003004.1, BC107697, BC107697.1, BC000319, NM_024348.4, NM_007234.5, NM_001281426.2, NM_001281427.2 |
| UniProt ID | O75935 |
| Summary | This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2013 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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