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Endothelin 3 (EDN3) Human shRNA Plasmid Kit (Locus ID 1908)

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SKU
TL304846
EDN3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*

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Other products for "Endothelin 3 or NM_000114"

Specifications
Specifications
Product Data
Locus ID 1908
Synonyms ET-3; ET3; HSCR4; PPET3; WS4B
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components EDN3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 1908). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_000114, NM_001302455, NM_001302456, NM_207032, NM_207033, NM_207034, NM_207034.1, NM_207034.2, NM_207032.1, NM_207032.2, NM_000114.1, NM_000114.2, NM_207033.1, NM_207033.2, NM_001302456.1, NM_001302455.1, BC008876, BC008876.2, BC053866, BC053866.1, NM_207032.3, NM_001302456.2, NM_001302455.2, NM_207034.3, NM_207033.3
UniProt ID P14138
Summary The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Oct 2014
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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