FOXP2 Human shRNA Plasmid Kit (Locus ID 93986)
Specifications
| Product Data | |
| Locus ID | 93986 |
|---|---|
| Synonyms | CAGH44; SPCH1; TNRC10 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | FOXP2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 93986). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001172766, NM_001172767, NM_001172777, NM_014491, NM_148898, NM_148899, NM_148900, NR_033766, NR_033767, NM_148898.1, NM_148898.2, NM_148898.3, NM_014491.1, NM_014491.2, NM_014491.3, NM_148899.1, NM_148899.2, NM_148899.3, NM_001172767.1, NM_001172767.2, NM_001172766.1, NM_001172766.2, NM_148900.1, NM_148900.2, NM_148900.3, NM_001172777.1, BC126104, BC018016, BC143866, BC143867, NM_014491.4, NM_001172766.3 |
| UniProt ID | O15409 |
| Summary | This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.provided by RefSeq, Feb 2010 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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