FOXP2 Human shRNA Plasmid Kit (Locus ID 93986)

SKU
TL304470
FOXP2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 93986
Synonyms CAGH44; SPCH1; TNRC10
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components FOXP2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 93986). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001172766, NM_001172767, NM_001172777, NM_014491, NM_148898, NM_148899, NM_148900, NR_033766, NR_033767, NM_148898.1, NM_148898.2, NM_148898.3, NM_014491.1, NM_014491.2, NM_014491.3, NM_148899.1, NM_148899.2, NM_148899.3, NM_001172767.1, NM_001172767.2, NM_001172766.1, NM_001172766.2, NM_148900.1, NM_148900.2, NM_148900.3, NM_001172777.1, BC126104, BC018016, BC143866, BC143867, NM_014491.4, NM_001172766.3
UniProt ID O15409
Summary This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.provided by RefSeq, Feb 2010
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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