ILF3 Human shRNA Plasmid Kit (Locus ID 3609)
Specifications
| Product Data | |
| Locus ID | 3609 |
|---|---|
| Synonyms | CBTF; DRBF; DRBP76; MMP4; MPHOSPH4; MPP4; MPP4110; NF-AT-90; NF90; NF90a; NF90b; NF90c; NF90ctv; NF110; NF110b; NFAR; NFAR-1; NFAR-2; NFAR2; NFAR90; NFAR110; TCP80; TCP110 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | ILF3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 3609). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001137673, NM_004516, NM_012218, NM_017620, NM_153464, NM_012218.1, NM_012218.2, NM_012218.3, NM_004516.1, NM_004516.2, NM_004516.3, NM_153464.1, NM_153464.2, NM_017620.2, NM_001137673.1, BC064836, BC001770, BC003086, BC014221, BC018633, BC048314, BM973331, NM_153464.3, NM_004516.4, NM_012218.4 |
| UniProt ID | Q12906 |
| Summary | This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.provided by RefSeq, Dec 2014 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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