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TET2 Human shRNA Plasmid Kit (Locus ID 54790)

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SKU
TL303734
TET2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
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Other products for "TET2 or NM_001127208"

Specifications
Specifications
Product Data
Locus ID 54790
Synonyms IMD75; KIAA1546; MDS
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components TET2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 54790). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001127208, NM_017628, NM_017628.1, NM_017628.2, NM_017628.3, NM_017628.4, NM_001127208.1, NM_001127208.2, BC019007, BC110509, BC110510, BC150180, BC150201, NM_001127208.3
UniProt ID Q6N021
Summary The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene. provided by RefSeq, Mar 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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Documents
Resources

file-alt Citations

Tet methylcytosine dioxygenase 2 inhibits atherosclerosis via upregulation of autophagy in ApoE-/- mice
Peng, Yang, Li et al
Oncotarget (2016) 7 (47), 76423-76436 DOI: 10.18632/oncotarget.13121
Snippet: HUVECs were seeded at 4×105 cells/well in a six-well plate and then transfected with 5 μg of TET2 overexpression plasmid or TET2 shRNA plasmid (OriGene Technologies Inc.) using Lipofectamine LTX (Invitrogen) in accordance with the manufacturer's instruction
FigureFigureFigure
Showing 1-1 of 1 papers.
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