L1CAM Human shRNA Plasmid Kit (Locus ID 3897)
Specifications
| Product Data | |
| Locus ID | 3897 |
|---|---|
| Synonyms | CAML1; CD171; HSAS; HSAS1; MASA; MIC5; N-CAM-L1; N-CAML1; NCAM-L1; S10; SPG1 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | L1CAM - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 3897). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_000425, NM_001143963, NM_001278116, NM_024003, NM_000425.1, NM_000425.2, NM_000425.3, NM_000425.4, NM_024003.1, NM_024003.2, NM_024003.3, NM_001143963.1, NM_001143963.2, NM_001278116.1, BC126229, BC025843, BC136447, NM_000425.5, NM_001278116.2 |
| UniProt ID | P32004 |
| Summary | The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. provided by RefSeq, May 2013 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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