LARGE (LARGE1) Human shRNA Plasmid Kit (Locus ID 9215)
Specifications
| Product Data | |
| Locus ID | 9215 |
|---|---|
| Synonyms | LARGE; MDC1D; MDDGA6; MDDGB6 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | LARGE1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 9215). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_004737, NM_133642, NM_004737.1, NM_004737.2, NM_004737.3, NM_004737.4, NM_004737.5, NM_133642.1, NM_133642.2, NM_133642.3, BC117425, BC126404, NM_001362949, NM_001362951, NM_001362953, NM_133642.5, NM_004737.7 |
| UniProt ID | O95461 |
| Summary | This gene encodes a member of the N-acetylglucosaminyltransferase gene family. It encodes a glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. It may also be involved in the addition of a repeated disaccharide unit. The protein encoded by this gene is the glycotransferase that adds the final xylose and glucuronic acid to alpha-dystroglycan and thereby allows alpha-dystroglycan to bind ligands including laminin 211 and neurexin. Mutations in this gene cause several forms of congenital muscular dystrophy characterized by cognitive disability and abnormal glycosylation of alpha-dystroglycan. Alternative splicing of this gene results in multiple transcript variants that encode the same protein. provided by RefSeq, May 2018 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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