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LRRFIP2 Human shRNA Plasmid Kit (Locus ID 9209)

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SKU
TL303432
LRRFIP2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 9209
Synonyms HUFI-2
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components LRRFIP2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 9209). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001134369, NM_001282691, NM_006309, NM_017724, NM_001348297, NM_001348298, NM_001348299, NM_001348300, NM_001348301, NM_001348302, NM_001348303, NM_001348304, NM_001348305, NM_001348306, NM_001348307, NM_001348308, NM_001348309, NM_001348310, NM_001348311, NR_145514, NM_017724.1, NM_017724.2, NM_006309.1, NM_006309.2, NM_006309.3, NM_001134369.1, NM_001134369.2, NM_001282691.1, BC053668, BC053668.1, NM_006309.4
UniProt ID Q9Y608
Summary The protein encoded by this gene, along with MYD88, binds to the cytosolic tail of toll-like receptor 4 (TLR4), which results in activation of nuclear factor kappa B signaling. The ubiquitin-like protein FAT10 prevents the interaction of the encoded protein and TLR4, thereby inactivating the nuclear factor kappa B signaling pathway. In addition, this protein can downregulate the NLRP3 inflammasome by recruiting the caspase-1 inhibitor Flightless-I to the inflammasome complex. provided by RefSeq, Jan 2017
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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