MAEL Human shRNA Plasmid Kit (Locus ID 84944)
Specifications
| Product Data | |
| Locus ID | 84944 |
|---|---|
| Synonyms | CT128; SPATA35 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | MAEL - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 84944). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001286377, NM_001286378, NM_032858, NM_032858.1, NM_032858.2, NM_001286378.1, NM_001286377.1, BC028595, BC028595.2, BC034310, NM_032858.3 |
| UniProt ID | Q96JY0 |
| Summary | Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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