MAX Human shRNA Plasmid Kit (Locus ID 4149)

SKU
TL303332
MAX - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
In Control Promo
  $1,013.00
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Specifications
Specifications
Product Data
Locus ID 4149
Synonyms bHLHd4
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components MAX - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 4149). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC003525, BC004516, NM_001271068, NM_001271069, NM_002382, NM_145112, NM_145113, NM_145114, NM_145116, NM_197957, NR_073137, NR_073138, NM_001320415, NM_145114.1, NM_145114.2, NM_145116.1, NM_145112.1, NM_145112.2, NM_002382.1, NM_002382.2, NM_002382.3, NM_002382.4, NM_197957.1, NM_197957.2, NM_197957.3, NM_145113.1, NM_145113.2, NM_001271068.1, NM_001271069.1, BC003525.1, BC004516.2, BC013669, BC036092, BC036092.1, BC025685, BC025685.1, BC027924, NM_002382.5, NM_145113.3, NM_145112.3, NM_001271069.2
UniProt ID P61244
Summary The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2012
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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