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KAT8 Human shRNA Plasmid Kit (Locus ID 84148)

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SKU
TL303060
KAT8 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
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Other products for "KAT8 or NM_032188"

Specifications
Specifications
Product Data
Locus ID 84148
Synonyms hMOF; LIGOWS; MOF; MYST1; ZC2HC8
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components KAT8 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 84148). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_032188, NM_182958, NM_182958.1, NM_182958.2, NM_032188.1, NM_032188.2, BC037773, NM_032188.3
UniProt ID Q9H7Z6
Summary This gene encodes a member of the MYST histone acetylase protein family. The encoded protein has a characteristic MYST domain containing an acetyl-CoA-binding site, a chromodomain typical of proteins which bind histones, and a C2HC-type zinc finger. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Feb 2012
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment
Urdinguio, Lopez, Bayón et al
Nucleic Acids Res. (2019) 47 (10), 5016-5037 DOI: 10.1093/nar/gkz195
AI Summary: OriGene contributed shKAT8 lentiviral expression vectors, which were used in this study to knock down KAT8 and investigate its role in histone H4K16 acetylation during myeloid cell differentiation and apoptosis.
Snippet: … Treatment with the HDAC inhibitor SAHA was carried out at 1 M for 48 h. The KAT8 overexpression vector was generated as previously described (48). … shKAT8 lentiviral expression vectors were obtained from OriGene (Rockville, MD). …
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Showing 1-1 of 1 papers.
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