OPA1 Human shRNA Plasmid Kit (Locus ID 4976)
Specifications
| Product Data | |
| Locus ID | 4976 |
|---|---|
| Synonyms | BERHS; largeG; MGM1; MTDPS14; NPG; NTG |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | OPA1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 4976). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_015560, NM_130831, NM_130832, NM_130833, NM_130834, NM_130835, NM_130836, NM_130837, NM_001354663, NM_001354664, NM_015560.1, NM_015560.2, NM_130831.1, NM_130831.2, NM_130832.1, NM_130832.2, NM_130834.1, NM_130834.2, NM_130837.1, NM_130837.2, NM_130835.1, NM_130835.2, NM_130833.1, NM_130833.2, NM_130836.1, NM_130836.2, BC075805, BC075805.1, BC035393, BC043443, BC058013, NM_130837.3, NM_130832.3, NM_130834.3, NM_130833.3, NM_130836.3 |
| UniProt ID | O60313 |
| Summary | The protein encoded by this gene is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. The encoded protein localizes to the inner mitochondrial membrane and helps regulate mitochondrial stability and energy output. This protein also sequesters cytochrome c. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. provided by RefSeq, Aug 2017 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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