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PANK2 Human shRNA Plasmid Kit (Locus ID 80025)

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SKU
TL302697
PANK2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*

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Other products for "PANK2 or NM_001324191"

Specifications
Specifications
Product Data
Locus ID 80025
Synonyms C20orf48; HARP; HSS; NBIA1; PKAN
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components PANK2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 80025). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001324191, NM_001324192, NM_001324193, NM_024960, NM_153637, NM_153638, NM_153639, NM_153640, NM_153641, NR_136715, NM_153638.1, NM_153638.2, NM_153638.3, NM_153640.1, NM_153640.2, NM_153640.3, NM_024960.1, NM_024960.2, NM_024960.3, NM_024960.4, NM_024960.5, NM_153637.1, BC009421, BC065019, BC093633, BC101569, BC101571, BC107724, BC142976, NM_024960.6
UniProt ID Q9BZ23
Summary This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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