PGC1 beta (PPARGC1B) Human shRNA Plasmid Kit (Locus ID 133522)

SKU
TL302354
PPARGC1B - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 133522
Synonyms ERRL1; PERC; PGC-1(beta); PGC1B
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components PPARGC1B - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 133522). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001172698, NM_001172699, NM_133263, NM_133263.1, NM_133263.2, NM_133263.3, NM_001172699.1, NM_001172698.1, BC026956, BC132971, BC132973, BC144251, NM_001172698.2
UniProt ID Q86YN6
Summary The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Mar 2010
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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