PTPRS Human shRNA Plasmid Kit (Locus ID 5802)

SKU
TL302192
PTPRS - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 5802
Synonyms PTPSIGMA; R-PTP-S; R-PTP-sigma
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components PTPRS - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 5802). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC029496, NM_002850, NM_130853, NM_130854, NM_130855, NM_130853.1, NM_130853.2, NM_002850.1, NM_002850.2, NM_002850.3, NM_130854.1, NM_130854.2, NM_130855.1, NM_130855.2, BC029496.1, BC104812, BC104812.1, BC143286, BC143287, BC148297, NM_130855.3, NM_002850.4, NM_130853.3, NM_130854.3
UniProt ID Q13332
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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