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SP1 Human shRNA Plasmid Kit (Locus ID 6667)

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SKU
TL301453
SP1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*

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Other products for "SP1 or NM_001251825"

Specifications
Specifications
Product Data
Locus ID 6667
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components SP1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 6667). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001251825, NM_003109, NM_138473, NM_138473.1, NM_138473.2, NM_003109.1, NM_001251825.1, BC062539, BC062539.1, BC012008, BC043224, BC078158, BM463205, NM_138473.3, NM_001251825.2
UniProt ID P08047
Summary The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Nov 2014
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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Documents
Resources

file-alt Citations

Resveratrol Represses Pokemon Expression in Human Glioma Cells
Yang, Cui, Xue et al
Molecular Neurobiology (2015)
AI Summary: OriGene contributed to this study by providing the Sp1 shRNA expression vector, which was used to investigate the role of Sp1 in regulating Pokemon expression in human glioma cells.
Snippet: N-terminus. Flag-tagged Sp1 mutated expression (resi- dues 703/A) vector was constructed by recombined PCR. Sp1 shRNA expression vector was purchased from Origene (Rockville, MD, USA). Lentiviral particles expressing ... Cite SaveSaving
Showing 1-1 of 1 papers.
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