THOC2 Human shRNA Plasmid Kit (Locus ID 57187)

SKU
TL301111
THOC2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 57187
Synonyms CXorf3; dJ506G2.1; hTREX120; MRX12; MRX35; THO2
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components THOC2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 57187). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001081550, NM_020449, NM_001081550.1, NM_020449.1, BC054050, BC063692, BC072400, BC172220, NM_001081550.2
UniProt ID Q8NI27
Summary The TREX multiprotein complex binds specifically to spliced mRNAs to facilitate mRNA export. The protein encoded by this gene is a member of the THO complex, a subset of the TREX complex. The encoded protein interacts with the THOC1 protein.provided by RefSeq, Jun 2010
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

THOC2 expression and its impact on 5-fluorouracil resistance in glioblastoma multiforme
Lee, Jung, Chang et al
Am J Cancer Res (2023) 13 (6), 2410-2425
AI Summary: OriGene products, specifically the THOC2 shRNA lentiviral vector (TL301111) and the control scrambled vector (TR30021), were used to knock down THOC2 expression in GBM cells, enabling the study of THOC2's role in 5-fluorouracil resistance.
Snippet: The green fluorescence protein (GFP) expressing THOC2 shRNA lentiviral vector TL301111 (Origene, Rockville, MD, USA) and control scrambled vector (TR30021, Origene) were transduced to T98FR with 8 µg/mL polybrene (Sigma-Aldrich)
Showing 1-1 of 1 papers.
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