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IKZF3 Human shRNA Plasmid Kit (Locus ID 22806)

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SKU
TL300029
IKZF3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
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Specifications
Specifications
Product Data
Locus ID 22806
Synonyms AIO; AIOLOS; ZNFN1A3
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components IKZF3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 22806). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001257408, NM_001257409, NM_001257410, NM_001257411, NM_001257412, NM_001257413, NM_001257414, NM_001284514, NM_001284515, NM_001284516, NM_012481, NM_183228, NM_183229, NM_183230, NM_183231, NM_183232, NR_047559, NR_047560, NR_047561, NM_012481.1, NM_012481.2, NM_012481.3, NM_012481.4, NM_183230.1, NM_183230.2, NM_183228.1, NM_183228.2, NM_183229.1, NM_183229.2, NM_183231.1, NM_183232.1, NM_183232.2, NM_001257413.1, NM_001257412.1, NM_001257411.1, NM_001257410.1, NM_001257414.1, NM_001257409.1, NM_001257408.1, NM_001284514.1, NM_001284515.1, NM_001284516.1, BC032707, BC032707.1, NM_183230.3, NM_183232.3, NM_001257412.2, NM_001257410.2, NM_012481.5, NM_001284515.2, NM_001257408.2, NM_001257409.2, NM_183229.3, NM_001257413.2, NM_183228.3, NM_183231.3, NM_001257411.2, NM_001257414.2
UniProt ID Q9UKT9
Summary This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. provided by RefSeq, Apr 2012
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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