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Cav3 Rat shRNA Plasmid (Locus ID 29161)

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SKU
TG710176
Cav3 - Rat, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 29161
Synonyms MGC105449
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Cav3 - Rat, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 29161). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_019155, NM_019155.1, NM_019155.2, BC084692
UniProt ID P51638
Summary regulates basal GTPase activity of purified heterotrimeric G-proteins and binds to and regulates the activity of endothelial nitric oxide synthase (eNOS); may play a role in stress fiber constriction in spleen sinus endothelial cells RGD, Feb 2006
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Cell surface expression of human ether-a-go-go-related gene (hERG) channels is regulated by caveolin-3 protein via the ubiquitin ligase Nedd4-2
Guo, Wang, Li et al
J. Biol. Chem. (2012) 287 (40), 33132-41 DOI: 10.1074/jbc.M112.389643
Cited by 7
AI Summary: OriGene products contributed to this study by providing the Cav3 plasmid and Myc-tagged Nedd4-1 plasmid, which were used to investigate the molecular interactions regulating hERG channel expression.
Snippet: delays cardiac repolarization and causes long QT syndrome (3). However, an increase in I hERG can cause short QT syndrome (4). Both long QT syndrome and short QT syndrome ... Cav3 plasmid and Myc-tagged plasmid of Nedd4-1 were obtained from Origene Technologies.
Showing 1-1 of 1 papers.
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