Wdr82 Mouse shRNA Plasmid (Locus ID 77305)
Specifications
| Product Data | |
| Locus ID | 77305 |
|---|---|
| Synonyms | 9430077D24Rik; CDW5/WDR82 |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Wdr82 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 77305). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | NM_029896, NM_029896.1, BC158054, BC019115, BC031502, BC044669, BC054453, BC094419, BC112907, BC157943, BC157945 |
| UniProt ID | Q8BFQ4 |
| Summary | Regulatory component of the SET1 complex implicated in the tethering of this complex to transcriptional start sites of active genes. Facilitates histone H3 'Lys-4' methylation via recruitment of the SETD1A or SETD1B to the 'Ser-5' phosphorylated C-terminal domain (CTD) of RNA polymerase II large subunit (POLR2A). Component of PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Possible role in telomere length maintenance and in mRNA processing (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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