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Lpar3 Mouse shRNA Plasmid (Locus ID 65086)

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SKU
TG517410
Lpar3 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 65086
Synonyms Edg7; lpA3
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Lpar3 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 65086). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq BC125460, BC125462, NM_022983, NM_022983.1, NM_022983.2, NM_022983.3, NM_022983.4
UniProt ID Q9EQ31
Summary Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Effects of lysophosphatidic acid (LPA) receptor-2 (LPA2) and LPA3 on the regulation of chemoresistance to anticancer drug in lung cancer cells
Ueda, Minami, Ishimoto et al
Cell. Signal. (2020) 69, 109551 DOI: 10.1016/j.cellsig.2020.109551
Cited by 40
AI Summary: OriGene's HuSH shRNA plasmid (29-mer) targeting LPA3 was used to generate LPA3 knockdown A549 lung cancer cells, enabling the study of LPA3's role in chemoresistance to anticancer drugs.
Snippet: 2.7. Generation of LPA 3 knockdown cells from A549 cells. Cells were transiently transfected with a HuSH shRNA plasmid (29-mer) against LPA 3 (Origene, Rockville, MD) using X-tremeGENE HP Transfection Reagent (Roche Diagnostics) and cultured
LPA signaling through LPA receptors regulates cellular functions of endothelial cells treated with anticancer drugs
Mori, Araki, Ishii et al
Mol. Cell. Biochem. (2015)
Cited by 4
AI Summary: OriGene’s HuSH short hairpin RNA plasmid targeting LPA receptors was used to suppress LPA receptor expression in F-2 cells, enabling the study of LPA signaling’s role in endothelial cell function during chemotherapy.
Snippet: Briefly, a HuSH short hairpin RNA plasmid (29-mer) against target LPA receptor (Origene, Rockville, MD) was transfected into F-2 cells using X-tremeGENE HP Trans- fection Reagent (Roche Diagnostics GmbH, Mannheim, Germany). ... Cite SaveSaving
Showing 1-2 of 2 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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