Wt1 Mouse shRNA Plasmid (Locus ID 22431)

SKU
TG516402
Wt1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 22431
Synonyms D630046I19Rik; Wt-1
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components Wt1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 22431). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq NM_144783, NM_144783.1, NM_144783.2, BC148376
Summary This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It plays an essential role in the normal development of the urogenital system, and the orthologous human gene is mutated in a small subset of patients with Wilm's tumors. Alternative splicing has been noted for this gene, however, the full-length nature of these variants is not known. The mRNA for this gene has been shown to initiate translation from non-AUG (CUG) and AUG translation start sites, resulting in different isoforms. provided by RefSeq, Apr 2013
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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