Capn2 Mouse shRNA Plasmid (Locus ID 12334)
Specifications
| Product Data | |
| Locus ID | 12334 |
|---|---|
| Synonyms | AI326419; Capa-2; Capa2; m-calpain; m-calpin |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Capn2 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 12334). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | BC054726, NM_009794, NM_009794.1, NM_009794.2, NM_009794.3, NM_009794.4 |
| UniProt ID | O08529 |
| Summary | Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (By similarity). Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs (PubMed:22711986).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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