Card11 Mouse shRNA Plasmid (Locus ID 108723)
Specifications
| Product Data | |
| Locus ID | 108723 |
|---|---|
| Synonyms | 0610008L17Rik; 2410011D02Rik; BIMP3; CARMA1 |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Card11 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 108723). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | BC096592, NM_175362, NM_175362.1, NM_175362.2 |
| UniProt ID | Q8CIS0 |
| Summary | Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation (PubMed:12356734, PubMed:16356855). Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10. Also activates the TORC1 signaling pathway (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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