Dock2 Mouse shRNA Plasmid (Locus ID 94176)
Specifications
| Product Data | |
| Locus ID | 94176 |
|---|---|
| Synonyms | AI662014; AW122239; CED-5; Hch; MBC |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Dock2 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 94176). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | NM_033374, NM_033374.1, NM_033374.2, NM_033374.3, BC040427, BC062272 |
| UniProt ID | Q8C3J5 |
| Summary | Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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