Zhx2 Mouse shRNA Plasmid (Locus ID 387609)
Specifications
| Product Data | |
| Locus ID | 387609 |
|---|---|
| Synonyms | Afr-1; Afr1; mKIAA0854; Raf |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Zhx2 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 387609). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | BC059178, NM_199449, NM_199449.1, NM_199449.2 |
| UniProt ID | Q8C0C0 |
| Summary | Acts as a transcriptional repressor (PubMed:19515908). Represses the promoter activity of the CDC25C gene stimulated by NFYA (By similarity). May play a role in retinal development where it regulates the composition of bipolar cell populations, by promoting differentiation of bipolar OFF-type cells (PubMed:30146259). In the brain, may promote maintenance and suppress differentiation of neural progenitor cells in the developing cortex (PubMed:19515908).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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