Bad Mouse shRNA Plasmid (Locus ID 12015)

SKU
TG510949
Bad - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 12015
Synonyms AI325008; Bbc2
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components Bad - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 12015). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq BC006762, NM_001285453, NM_007522, NM_007522.1, NM_007522.2, NM_007522.3, NM_001285453.1
UniProt ID Q61337
Summary Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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