Plxna2 Mouse shRNA Plasmid (Locus ID 18845)
Specifications
| Product Data | |
| Locus ID | 18845 |
|---|---|
| Synonyms | 2810428A13Rik; AA589422; AW457381; mKIAA0463; OCT; PlexA2; Plxn2 |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Plxna2 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 18845). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | BC068155, NM_008882, NM_008882.1, NM_008882.2, BC024509, BC051045, BC056475 |
| UniProt ID | P70207 |
| Summary | Coreceptor for SEMA3A and SEMA6A. Necessary for signaling by SEMA6A and class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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