Arcn1 Mouse shRNA Plasmid (Locus ID 213827)
Specifications
| Product Data | |
| Locus ID | 213827 |
|---|---|
| Synonyms | 4632432M07Rik; nur17 |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Arcn1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 213827). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | BC017124, BC023728, BC033387, BC034754, BC083152, NM_145985, NM_145985.1, NM_145985.2, NM_145985.3, NM_145985.4, BC008236, BC024127, BC050874 |
| UniProt ID | Q5XJY5 |
| Summary | The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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