Tdrd3 Mouse shRNA Plasmid (Locus ID 219249)
Specifications
| Product Data | |
| Locus ID | 219249 |
|---|---|
| Synonyms | 4732418C03Rik; 6720468N18 |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Tdrd3 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 219249). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | BC005670, BC066144, NM_001253755, NM_172605, NM_172605.1, NM_172605.2, NM_172605.3, NM_001253755.1 |
| UniProt ID | Q91W18 |
| Summary | Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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