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Acly Mouse shRNA Plasmid (Locus ID 104112)

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SKU
TG505684
Acly - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
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Specifications
Specifications
Product Data
Locus ID 104112
Synonyms A730098H14Rik; AW538652
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Acly - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 104112). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq BC056378, NM_001199296, NM_134037, NM_134037.1, NM_134037.2, NM_134037.3, NM_001199296.1, BC005533, BC021502, BC065805
UniProt ID Q91V92
Summary ATP-citrate synthase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis (PubMed:25450640). In nervous tissue it may be involved in the biosynthesis of acetylcholine (By similarity) (PubMed:25450640).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

ATP-citrate lyase reduction mediates palmitate-induced apoptosis in pancreatic beta cells
Chu, Lin, Hendel et al
J Biol Chem (2010) 285 (42), 32606-15 DOI: 10.1074/jbc.M110.157172
AI Summary: OriGene products contributed to this study by providing ACLY shRNA (OriGene, TL500847) for gene knockdown experiments and ACLY cDNA (OriGene, MR201088) for overexpression studies, enabling the authors to assess the role of ATP-citrate lyase in palmitate-induced apoptosis in pancreatic beta cells.
Showing 1-1 of 1 papers.
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