Crbn Mouse shRNA Plasmid (Locus ID 58799)
Specifications
| Product Data | |
| Locus ID | 58799 |
|---|---|
| Synonyms | 2610203G15Rik; 2900045O07Rik; AF229032; AW108261; piL |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Crbn - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 58799). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | BC086488, NM_021449, NM_175357, NM_175357.1, NM_175357.2, NM_175357.3, NM_021449.1, NM_021449.2, NM_021449.3, BC033458, BC046967, BC069905 |
| UniProt ID | Q8C7D2 |
| Summary | This gene encodes a protein with a Lon protease domain, a "regulators of G protein-signaling" (RGS)-like domain and a leucine zipper. It has been proposed to regulate the assembly and surface expression of large-conductance calcium-activated potassium channels in brain and to bind thalidomide. In humans mutation in this gene causes autosomal recessive nonsyndromic cognitive disability. In mouse deficiency of this gene serves as a model to study the molecular mechanisms governing learning and memory as they relate to intellectual disability. Alternative splicing results in multiple transcript variants that encode different protein isoforms. provided by RefSeq, Jan 2013 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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