Sphk2 Mouse shRNA Plasmid (Locus ID 56632)

SKU
TG503229
Sphk2 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 56632
Synonyms C76851; Sk2; Spk2
Vector pGFP-V-RS
E. coli Selection Kanamycin
Format Retroviral plasmids
Components Sphk2 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 56632). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq BC006941, BC053737, BC092084, NM_001172561, NM_020011, NM_203280, NM_020011.1, NM_020011.2, NM_020011.3, NM_020011.4, NM_020011.5, NM_001172561.1, NM_203280.1, NM_203280.2, NM_203280.3
UniProt ID Q9JIA7
Summary This gene encodes a kinase that phosphorylates sphingosine into sphingosine-1-phosphate, which is involved in cell differentiation, motility, and apoptosis. The encoded protein plays a role in maintaining cellular levels of sphingosine-1-phosphate. The gene product also enhances apoptosis in different cell types and suppresses cellular proliferation. In mast cells, the encoded protein is necessary for influx of calcium, protein kinase C activation, and cytokine production and degranulation. Alternative splicing results in multiple transcript variants. provided by RefSeq, Feb 2010
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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