Hs2st1 Mouse shRNA Plasmid (Locus ID 23908)
Specifications
| Product Data | |
| Locus ID | 23908 |
|---|---|
| Synonyms | 2OST; AW214369; Hs2st; mKIAA0448 |
| Vector | pGFP-V-RS |
| E. coli Selection | Kanamycin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Hs2st1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 23908). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
| RefSeq | BC025443, BC059008, NM_011828, NM_001355234, NM_011828.1, NM_011828.2, NM_011828.3, BC016560 |
| UniProt ID | Q8R3H7 |
| Summary | Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS). 2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high-affinity ligand-binding interactions and signaling processes. Required for metanephric development of kidney formation, suggesting that 2-O-sulfation within HS is essential for signaling between ureteric bud and metanephric mesenchyme. Mediates 2-O-sulfation of both L-iduronyl and D-glucuronyl residues.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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