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Xrcc1 Mouse shRNA Plasmid (Locus ID 22594)

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SKU
TG502434
Xrcc1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 22594
Synonyms Xrcc-1
Vector pGFP-V-RS
E. coli Selection Kanamycin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Xrcc1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 22594). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
RefSeq BC055900, BC085281, NM_009532, NM_001360170, NM_009532.1, NM_009532.2, NM_009532.3, NM_009532.4, NM_001360168, NM_001360169, NM_009532.5
UniProt ID Q60596
Summary Involved in DNA single-strand break repair by mediating the assembly of DNA break repair protein complexes (By similarity). Probably during DNA repair, negatively regulates ADP-ribose levels by modulating ADP-ribosyltransferase PARP1 activity (PubMed:28002403).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Nuclear Localization of the DNA Repair Scaffold XRCC1: Uncovering the Functional Role of a Bipartite NLS
Kirby, Gassman, Smith et al
Sci Rep (2015) 5, 13405 DOI: 10.1038/srep13405
Cited by 37
AI Summary: OriGene contributed to this study by providing the human XRCC1 with a C-terminal GFP fusion construct (catalog number RG204952, pCMV-AC-GFP), which was used to investigate the nuclear localization and functional role of XRCC1’s bipartite NLS.
Snippet: kit (Lonza, Rockland, ME) and results were negative. Human XRCC1 with a C-terminal GFP (RG204952, pCMV-AC-GFP) was purchased from Origene (Rockville, MD). Site-directed mutagenesis was utilized to create XRCC1 ... Cite SaveSaving
FigureFigureFigure
Showing 1-1 of 1 papers.
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